Relapse of neuromyelitis optica associated with oral progestin.

نویسندگان

  • Li-Min Li
  • Chao Zhang
  • Lin-Jie Zhang
  • Hui-Yue Guo
  • Chun-Sheng Yang
  • Rui Zhang
  • Yu-Jing Li
  • Fu-Dong Shi
  • Li Yang
چکیده

J Neurol Neurosurg Psychiatry Month 2017 Vol 0 No 0 Figure 1 The clinical, paraclinical course and therapeutic regimens of a female patient with NMO. (A) Timeline of NMO and therapeutic regimens. (B) November 2002: sagittal T2-weighted image of spinal cord exhibits hyperintense lesions in the thoracic spinal cord from the T2 to T4 levels. Axial brain MRI scan shows corticospinal tract lesions involving the posterior limb of the internal capsule and periventricular area on T2-weighted sequence. (C) October 2016: fat-saturated T2-weighted axial (above) and coronal (below) images show left optic nerve enlargement with hyperintensity. NMO, neuromyelitis optica; ON, optic neuritis; HDMP, high-dose methylprednisolone; red ◊ symbols, period of high-dose methylprednisolone use; red horizontal lines, period of oral prednisone treatment; blue horizontal lines, period of oral azathioprine treatment. LeTTeR

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Relapse of Neuromyelitis Optica Spectrum Disorder Associated with Intravenous Lidocaine

Lidocaine unmasks silent symptoms and eases neuropathic pain in multiple sclerosis patients; however, the effects of lidocaine in neuromyelitis optica have never been reported. We describe the case of a 59-year-old Japanese woman with neuromyelitis optica spectrum disorder who developed optic neuritis 1 day after intravenous lidocaine injection for treating allodynia. Her symptom seemed to resu...

متن کامل

Enhancing Brain Lesions during Acute Optic Neuritis and/or Longitudinally Extensive Transverse Myelitis May Portend a Higher Relapse Rate in Neuromyelitis Optica Spectrum Disorders.

BACKGROUND AND PURPOSE Neuromyelitis optica spectrum disorders are inflammatory demyelinating disorders with optic neuritis and/or longitudinally extensive transverse myelitis episodes. We now know that neuromyelitis optica spectrum disorders are associated with antibodies to aquaporin-4, which are highly concentrated on astrocytic end-feet at the blood-brain barrier. Immune-mediated disruption...

متن کامل

Neuromyelitis Optica in Children: A Rare Entity

     Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

متن کامل

Failure of autologous hematopoietic stem cell transplantation to prevent relapse of neuromyelitis optica.

H ere we describe a woman with relapsing neuromyelitis optica (NMO) who was seropositive for NMO-IgG and who experienced a relapse of myelitis 4 months after autologous hematopoietic stem cell transplantation (AHSCT) for a lymphoma that developed while receiving azathioprine therapy. Analysis of serum samples obtained at key points in her disease course using 3 different serological techniques ...

متن کامل

O 11: Diagnosis and Management of Neuromyelitis Optica

Typical NMO is characterized by simultaneous or sequential acute transverse myelitis and optic neuritis. Spinal cord lesions extending over 3 or more vertebral segments and normal brain imaging are the typical MRI findings in NMO. In typical cases with positive NMO antibody the diagnosis is easy but in seronegative and atypical cases with different clinical manifestations and MRI features the d...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره   شماره 

صفحات  -

تاریخ انتشار 2017